NS-398
description
Additional Information
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Applications:
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FA
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Synonyms:
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NS398, NS 398
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Formulation:
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Crystalline solid
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Chemical Name:
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N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
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Molecular Formula:
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C13H18N2O5S |
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Molecular Weight: |
314.4
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CAS Number
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123653-11-2
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at room temperature.
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References:
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Futaki, N., Yoshikawa, K., Hamasaka, Y., Arai, I., Higuchi, S., Iizuka, H., & Otomo, S. (1993). NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. General Pharmacology: The Vascular System, 24(1), 105-110. Futaki, N., Takahashi, S., Yokoyama, M., Arai, I., Higuchi, S., & Otomo, S. (1994). NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro.Prostaglandins, 47(1), 55-59. Joki, T., Heese, O., Nikas, D. C., Bello, L., Zhang, J., Kraeft, S. K., ... & Black, P. M. (2000). Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398. Cancer research,60(17), 4926-4931. |