Nocodazole

Grouped product items
SizePrice Qty
10mg
$65.00
50mg
$215.00
Catalog Number : 3141890

description

Nocodazole is an antineoplastic microtubule polymerization inhibitor. It is frequently used to synchronize cell cycling and arrest cells with a G2- or M- phase DNA content. It is reported to enhance homology-directed repair (HDR) efficiency and increase Cas9-mediated editing frequencies.
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Additional Information

Applications:
FA
Synonyms:
Nocodazolum, ChEMBL9514, Oncodazole
Formulation:
Crystalline solid
Chemical Name:
methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
Molecular Formula:

C14H11N3O3S

Molecular Weight:
301.3
CAS Number
31430-18-9
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Vasquez, R. J., Howell, B., Yvon, A. M., Wadsworth, P., & Cassimeris, L. (1997). Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Molecular biology of the cell8(6), 973-985.

Yang, D., Scavuzzo, M. A., Chmielowiec, J., Sharp, R., Bajic, A., & Borowiak, M. (2016). Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases. Scientific reports6.

Lin, S., Staahl, B. T., Alla, R. K., & Doudna, J. A. (2014). Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery. Elife3, e04766.

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