Nelfinavir mesylate

Grouped product items
SizePrice Qty
10mg
$75.00
50mg
$300.00
Catalog Number : 1596589

description

Nelfinavir is a potent competitive inhibitor of the HIV-1 protease. It is reported that it can also inhibit the growth of various cell types and trigger apoptosis.
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Additional Information

Applications:
FA
Synonyms:
AG-1343, AG1343, Viracept
Formulation:
Crystalline solid
Chemical Name:
(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide;methanesulfonic acid
Molecular Formula:

C32H45N3O4S CH3SO3H

Molecular Weight:
663.9
CAS Number
159989-65-8
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Kaldor, S. W., Kalish, V. J., Davies, J. F., Shetty, B. V., Fritz, J. E., Appelt, K., ... & Dressman, B. A. (1997). Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease. Journal of medicinal chemistry40(24), 3979-3985.

Dube, M. P., Parker, R. A., Tebas, P., Grinspoon, S. K., Zackin, R. A., Robbins, G. K., ... & Snyder, S. W. (2005). Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides. Aids19(16), 1807-1818.

Gills, J. J., LoPiccolo, J., & Dennis, P. A. (2008). Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy.Autophagy4(1), 107-109.

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