NBQX disodium salt

Grouped product items
SizePrice Qty
10mg
$140.00
50mg
$500.00
Catalog Number : 4798694

description

NBQX is a potent and selective AMPA and kainate receptor antagonist that is used to counter glutamate excitotoxicity. It is reported to exhibit anticonvulsant activity in rodent models. NBQX disodium salt is the more water soluble version of this reagent.
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Additional Information

Applications:
FA
Synonyms:
1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt, FG9202 disodium
Formulation:
Crystalline solid
Chemical Name:
disodium;6-nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-diolate
Molecular Formula:

C12H6N4O6S 2Na

Molecular Weight:
380.2
CAS Number
479347-86-9
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Chapman, A. G., Smith, S. E., & Meldrum, B. S. (1991). The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice.Epilepsy research9(2), 92-96.

Gill, R., Nordholm, L., & Lodge, D. (1992). The neuroprotective actions of 2, 3-dihydroxy-6-nitro-7-sulfamoyl-benzo (F) quinoxaline (NBQX) in a rat focal ischaemia model. Brain research580(1), 35-43.

Wrathall, J. R., Choiniere, D., & Teng, Y. D. (1994). Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX. The Journal of neuroscience,14(11), 6598-6607.

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