Metformin hydrochloride

Grouped product items
SizePrice Qty
1g
$25.00
5g
$35.00
Catalog Number : 1117045

description

Metformin is an activator of the AMPK pathway and is reported to decrease hyperglycemia by the suppression of liver glucose production. Metformin improves insulin sensitivity and lower plasma glucose levels. It is reported to promote neurogenesis and exhibits an anti-proliferative effect in cancer lines.
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Additional Information

Applications:
FA
Synonyms:
Dimethylbiguanidine, Dimethylguanylguanidine, Glucophage, Metformin
Formulation:
Crystalline solid
Chemical Name:
3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride
Molecular Formula:

C4H11NHCl

Molecular Weight:
165.6
CAS Number
1115-70-4
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Evans, J. M., Donnelly, L. A., Emslie-Smith, A. M., Alessi, D. R., & Morris, A. D. (2005). Metformin and reduced risk of cancer in diabetic patients. Bmj,330(7503), 1304-1305.

Hirsch, H. A., Iliopoulos, D., & Struhl, K. (2013). Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proceedings of the National Academy of Sciences110(3), 972-977.

Viollet, B., Guigas, B., Garcia, N. S., Leclerc, J., Foretz, M., & Andreelli, F. (2012). Cellular and molecular mechanisms of metformin: an overview.Clinical science122(6), 253-270.

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