LY294002

Grouped product items
SizePrice Qty
5mg
$40.00
25mg
$170.00
Catalog Number : 1543664

description

LY294002 is a morpholine-containing potent reversible inhibitor of phosphoinositide 3-kinases (PI3Ks) and BETproteins. It is reported to be promote the differentiation of insulin-producing cells from embryonic cells and inhibit the growth of ovarian carcinomas.
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Additional Information

Applications:
FA
Synonyms:
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, LY-294002
Formulation:
Crystalline solid
Chemical Name:
2-morpholin-4-yl-8-phenylchromen-4-one
Molecular Formula:

C19H17NO3

Molecular Weight:
307.3
CAS Number
154447-36-6
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Gharbi, S., Zvelebil, M., Shuttleworth, S., Hancox, T., Saghir, N., Timms, J., & Waterfield, M. (2007). Exploring the specificity of the PI3K family inhibitor LY294002. Biochem. J404, 15-21.

Vlahos, C. J., Matter, W. F., Hui, K. Y., & Brown, R. F. (1994). A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). Journal of Biological Chemistry269(7), 5241-5248.

Sanchezmargalet, V., Goldfine, I. D., Vlahos, C. J., & Sung, C. K. (1994). Role of phosphatidylinositol-3-kinase in insulin receptor signaling: studies with inhibitor, LY294002. Biochemical and biophysical research communications,204(2), 446-452

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