Hydroxychloroquine sulfate

Grouped product items
SizePrice Qty
50mg
$45.00
250mg
$195.00
Catalog Number : 7473646

description

Hydroxychloroquine sulfate is a synthetic quinolyl derivative that is commonly used as an antimalarial agent. It is reported to increase lysosomal pH in antigen presenting cells, inhibit autophagy and block toll-like receptors on plasmacytoid dendritic cells (PDCs). Hydroxychloroquine sulfate reduces the activation of dendritic cells and the inflammatory process. It is currently being researched as a potential treatment for COVID-19.
product image

Additional Information

Applications:
FA
Synonyms:
Hydroxychlorochin, Oxychloroquine, Plaquenil, HCQ sulfate
Formulation:
Crystalline solid
Chemical Name:
2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid
Molecular Formula:

C18H26ClN3O H2SO4

Molecular Weight:
434.0
CAS Number
747-36-4
Purity:
95%
Storage Conditions:
Product should be kept at -20°C.
References:

Ben-Zvi, I., Kivity, S., Langevitz, P., & Shoenfeld, Y. (2012). Hydroxychloroquine: from malaria to autoimmunity. Clinical reviews in allergy & immunology42(2), 145-153.

Gao, J., Tian, Z., & Yang, X. (2020). Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies. BioScience Trends.

Torigoe, M., Sakata, K., Ishii, A., Iwata, S., Nakayamada, S., & Tanaka, Y. (2018). Hydroxychloroquine efficiently suppresses inflammatory responses of human class-switched memory B cells via Toll-like receptor 9 inhibition. Clinical Immunology195, 1-7.

© BioGems International, Inc. All rights reserved.