Go 6983

Grouped product items
SizePrice Qty
1mg
$40.00
10mg
$200.00
Catalog Number : 1331975

description

Go 6983 is a broad fast-acting inhibitor of various isoforms of protein kinase C. It can be used to inhibit differentiation and maintain the pluripotency of embryonic stem cells and enhance stem cell viability and growth. Go 6983 is also reported to exert cardio protective effects in myocardial ischemia and inhibited intracellular Ca accumulation.
product image

Additional Information

Applications:
FA
Synonyms:
Gö6983, Gö 6983, 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide
Formulation:
Crystalline solid
Chemical Name:
3-[1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
Molecular Formula:

C26H26N4O3

Molecular Weight:
442.5
CAS Number
133053-19-7
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Peterman, E. E., & Taormina, P. II, Harvey, M., and Young, LH 2004. Go 6983 exerts cardioprotective effects in myocardial ischemia/reperfusion. J. Cardiovasc. Pharmacol43, 645-656.

Young, L. H., Balin, B. J., & Weis, M. T. (2005). Gö 6983: a fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury.Cardiovascular drug reviews23(3), 255-272.

Gschwendt, M., Dieterich, S., Rennecke, J., Kittstein, W., Mueller, H. J., & Johannes, F. J. (1996). Inhibition of protein kinase C μ by various inhibitors. Inhibition from protein kinase c isoenzymes. FEBS letters392(2), 77-80.

 

© BioGems International, Inc. All rights reserved.