Ciclesonide
Catalog Number : 1264764
description
Ciclesonide is a glucocorticoid anti-asthmatic prodrug that is cleaved by endogenous esterases to the active form in the lungs. It is typically used as a treatment for obstructive airway diseases and exhibits anti-inflammatory properties. It is currently being researched as a potential treatment for COVID-19.
Additional Information
Applications:
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FA
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Synonyms:
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Omnaris, Alvesco, Zetonna, Osonase
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Formulation:
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Crystalline solid
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Chemical Name:
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[2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] 2-methylpropanoate
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Molecular Formula:
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C32H44O7 |
Molecular Weight: |
540.7
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CAS Number
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126544-47-6
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Purity:
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98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Reynolds, N. A., & Scott, L. J. (2004). Ciclesonide. Drugs, 64(5), 511-519. Keller, K. D. R. E. A. (2001). Ciclesonide: an on-site-activated steroid. New drugs for asthma, allergy and COPD, 31, 91-93. Matsuyama, S., Kawase, M., Nao, N., Shirato, K., Ujike, M., Kamitani, W., ... & Fukushi, S. (2020). The inhaled corticosteroid ciclesonide blocks coronavirus RNA replication by targeting viral NSP15. bioRxiv. |