Camostat mesylate

Grouped product items
SizePrice Qty
10mg
$50.00
50mg
$165.00
Catalog Number : 5972981

description

Camostat mesylate is a glycosylphosphatidylinositol-anchored serine protease inhibitor. It inhibits airway epithelial sodium channel function and it is reported to inhibit the generation of TGF-beta. It is currently being researched as a potential treatment for COVID-19.
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Additional Information

Applications:
FA
Synonyms:
camostate-mesilate, FOY 305, foypan
Formulation:
Crystalline solid
Chemical Name:
[4-[2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl]phenyl] 4-(diaminomethylideneamino)benzoate;methanesulfonic acid
Molecular Formula:

C20H22N4O5 CH3SO3H

Molecular Weight:
494.5
CAS Number
59721-29-8
Purity:
98%
Storage Conditions:
Product should be kept at -20°C.
References:

Coote, K., Atherton-Watson, H. C., Sugar, R., Young, A., MacKenzie-Beevor, A., Gosling, M., ... & Sabater, J. R. (2009). Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease. Journal of Pharmacology and Experimental Therapeutics329(2), 764-774.

Gibo, J., Ito, T., Kawabe, K., Hisano, T., Inoue, M., Fujimori, N., ... & Nawata, H. (2005). Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. Laboratory investigation85(1), 75-89.

Yang, N., & Shen, H. M. (2020). Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19. Int J Biol Sci16(10), 1724-1731.

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