Docosahexaenoic acid (DHA)
Catalog Number : 6215455
description
Docosahexaenoic acid is an essential omega-3 fatty acid that is the primary structural component of the nervous system, skin, testicles and retina. Among its functions are to modulate the carrier-mediated transport of glycine, taurine, and choline and its deficiency is linked with neural cell death and cognitive decline. It is reported to be a ligand for the retinoid X receptor (RXR) in mouse brain tissue.
Additional Information
Applications:
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FA
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Synonyms:
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Docosahexaenoate
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Formulation:
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Ethanol Solution
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Chemical Name:
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(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid
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Molecular Formula:
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C22H32O2 |
Molecular Weight: |
328.5
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CAS Number
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6217-54-5
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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de Urquiza, A. M., Liu, S., Sjöberg, M., Zetterström, R. H., Griffiths, W., Sjövall, J., & Perlmann, T. (2000). Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science, 290(5499), 2140-2144. Salem Jr, N., Litman, B., Kim, H. Y., & Gawrisch, K. (2001). Mechanisms of action of docosahexaenoic acid in the nervous system. Lipids, 36(9), 945-959. Corey, E. J., Shih, C., & Cashman, J. R. (1983). Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis. Proceedings of the National Academy of Sciences, 80(12), 3581-3584. |