Chloroquine diphosphate
Catalog Number : 5066350
description
Chloroquine is a 4-aminoquinoline that is commonly used as an antimalarial agent. It exhibits anti-cancer properties in numerous cancer cell lines and antimetastatic activity. Chloroquine is reported to inhibit autophagy and cell proliferation. It is currently being researched as a potential treatment for COVID-19.
Additional Information
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Applications:
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FA
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Synonyms:
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chingamin, Aralen
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Formulation:
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Crystalline solid
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Chemical Name:
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4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoric acid
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Molecular Formula:
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C18H26ClN3 2H3PO4 |
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Molecular Weight: |
515.9
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CAS Number
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50-63-5
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Purity:
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95%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Krogstad, D. J., Gluzman, I. Y., Kyle, D. E., Oduola, A. M., Martin, S. K., Milhous, W. K., & Schlesinger, P. H. (1987). Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. Science, 238(4831), 1283-1285. Kimura, T., Takabatake, Y., Takahashi, A., & Isaka, Y. (2013). Chloroquine in cancer therapy: a double-edged sword of autophagy. Cancer research, 73(1), 3-7. Gao, J., Tian, Z., & Yang, X. (2020). Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies. BioScience Trends. |