(+)-BAY-K-8644
Catalog Number : 9876741
description
(+)-BAY-K-8644 is a L-type calcium channel agonist with negative vasodilatory and inotropic effects. The (+)-BAY-K-8644 enantiomer exhibits opposite biological effects to the racemate and (-)-BAY-K-8644 molecules.
Additional Information
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Applications:
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FA
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Synonyms:
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(R)-(+)-BAY K 8644; CHEMBL105672; (R)-(+)-Bay K8644; methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
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Formulation:
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Crystalline solid
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Chemical Name:
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methyl (4R)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
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Molecular Formula:
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C16H15F3N2O4 |
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Molecular Weight: |
356.3
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CAS Number
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98791-67-4
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at-20°C.
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References:
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Garcia, A. G., Sala, F., Reig, J. A., Viniegra, S., Frias, J., Fonteriz, R., & Gandia, L. (1984). Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels. Franckowiak, G., Bechem, M., Schramm, M., & Thomas, G. (1985). The optical isomers of the 1, 4-dihydropyridine BAY K 8644 show opposite effects on Ca channels. European journal of pharmacology, 114(2), 223-226. Yamamoto, H., Hwang, O. K., & Van Breeman, C. (1984). Bay K8644 differentiates between potential and receptor operated Ca 2+ channels.European journal of pharmacology, 102(3), 555-557. |