Puromycin dihydrochloride

Grouped product items
SizePrice Qty
50mg
$50.00
500mg
$375.00
Catalog Number : 5855822

description

Puromycin is an aminonucleoside antibiotic and protein synthesis inhibitor. It is a reversible inhibitor of dipeptidyl-pepdidase II (serine peptidase) and cytosol alanyl aminopeptidase. Puromycin functions by inhibiting translation and it also inhibits the transportation of protein into the mitochondria.
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Additional Information

Applications:
FA
Synonyms:
Puromycin HCl, Stylomycin hydrochloride, CL13900, P-638
Formulation:
Crystalline solid
Chemical Name:
(2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide;dihydrochloride
Molecular Formula:

C22H29N7O5 2HCl

Molecular Weight:
544.4
CAS Number
58-58-2
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:

Traut, R. R., & Monro, R. E. (1964). The puromycin reaction and its relation to protein synthesis. Journal of molecular biology10(1), 63-72.

Okita, K., Nakagawa, M., Hyenjong, H., Ichisaka, T., & Yamanaka, S. (2008). Generation of mouse induced pluripotent stem cells without viral vectors.Science322(5903), 949-953.

Vara, J. A., Portela, A., Ortìn, J., & Jimenez, A. (1986). Expression in mammalian cells of a gene from Streptomyces alboniger conferring puromycin resistance. Nucleic acids research14(11), 4617-4624.

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