Gatifloxacin
Catalog Number : 1125931
description
Gatifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. It is potent against gram positive and gram negative bacteria and is reported to promote self-renewal in cultured embryonic stem cells.
Additional Information
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Applications:
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FA
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Synonyms:
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AM-1155, gatifloxacine, Tequin, Zymar
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Formulation:
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Crystalline solid
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Chemical Name:
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1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
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Molecular Formula:
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C19H22FN3O4 |
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Molecular Weight: |
375.4
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CAS Number
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112811-59-3
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Purity:
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≥98%
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Storage Conditions:
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Product should be kept at -20°C.
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References:
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Perry, C. M., Balfour, J. A. B., & Lamb, H. M. (1999). Gatifloxacin. Drugs,58(4), 683-696. Fung-Tomc, J., Minassian, B., Kolek, B., Washo, T., Huczko, E., & Bonner, D. (2000). In vitro antibacterial spectrum of a new broad-spectrum 8-methoxy fluoroquinolone, gatifloxacin. Journal of Antimicrobial Chemotherapy, 45(4), 437-446. Desbordes, S. C., Placantonakis, D. G., Ciro, A., Socci, N. D., Lee, G., Djaballah, H., & Studer, L. (2008). High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell stem cell, 2(6), 602-612. |