Doxycycline hyclate

Grouped product items
Size	Price	Qty
1g	$35.00
10g	$145.00

Catalog Number : 2431450

description

Doxycycline is a synthetic oxytetracycline broad-spectrum antibiotic, used to treat a variety of infections such as Lyme disease, Rickettsia, Brucella melitensis, Chlamydia pneumoniae, and others. It is also an inhibitor of matrix metalloproteases and useful in regulating inducible gene expression in Tet-ON/Off systems.

Additional Information

Applications:	FA
Synonyms:	alpha 6 Deoxyoxytetracycline, Atridox, Hydramycin, Doxycycline hydrochloride hemiethanolate hemihydrate
Formulation:	Crystalline solid
Chemical Name:	(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;ethanol;hydrate;dihydrochloride
Molecular Formula:	2 x [C₂₂H₂₄N₂O₈ 2HCl] H₂O C₂H₆O
Molecular Weight:	1025.9
CAS Number	24390-14-5
Purity:	≥98%
Storage Conditions:	Product should be kept at -20°C.
References:	Kistner, A., Gossen, M., Zimmermann, F., Jerecic, J., Ullmer, C., Lübbert, H., & Bujard, H. (1996). Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proceedings of the National Academy of Sciences, 93(20), 10933-10938. Nadelman, R. B., Nowakowski, J., Fish, D., Falco, R. C., Freeman, K., McKenna, D., ... & Wormser, G. P. (2001). Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite. New England Journal of Medicine, 345(2), 79-84. Hanemaaijer, R., Visser, H., Koolwijk, P., Sorsa, T., Salo, T., Golub, L. M., & Van Hinsbergh, V. W. M. (1998). Inhibition of MMP synthesis by doxycycline and chemically modified tetracyclines (CMTs) in human endothelial cells.Advances in Dental Research, 12(1), 114-118.