KRN 7000

Grouped product items
SizePrice Qty
250ug
$130.00
1mg
$340.00
Catalog Number : 1584771

description

KRN 7000 is a potent activator of NKT cells and CD1d ligand that was originally isolated from the murine sponge Agelas mauritianus. It exhibits immunostimulant and anti-tumor properties and is also reported to protect against LPS-induced shock.
product image

Additional Information

Applications:
FA
Synonyms:
KRN7000, alpha-GalCer, alpha-Galactosylceramide
Formulation:
Crystalline solid
Chemical Name:
N-[(2S,3S,4R)-3,4-dihydroxy-1-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadecan-2-yl]hexacosanamide
Molecular Formula:

C50H99NO9

Molecular Weight:
858.3
CAS Number
158021-47-7
Purity:
≥96%
Storage Conditions:
Product should be kept at -20°C.
References:

Banchet-Cadeddu, A., Hénon, E., Dauchez, M., Renault, J. H., Monneaux, F., & Haudrechy, A. (2011). The stimulating adventure of KRN 7000. Organic & biomolecular chemistry9(9), 3080-3104.

Kobayashi, E., Motoki, K., Uchida, T., Fukushima, H., & Koezuka, Y. (1995). KRN7000, a novel immunomodulator, and its antitumor activities. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics7(10-11), 529-534.

Hayakawa, Y., Rovero, S., Forni, G., & Smyth, M. J. (2003). α-Galactosylceramide (KRN7000) suppression of chemical-and oncogene-dependent carcinogenesis. Proceedings of the National Academy of Sciences100(16), 9464-9469.

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