Creating Value for Life Science Research!


Get a Free Sample of this product!
shopping cart image

Recombinant Rat Leptin



Catalog Number : 400-21

Description

Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant Rat Leptin is a 16.2 kDa protein containing 147 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Mouse
 
Biological Activity
Determined by an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5µg leptin/gm of body weight for 7 days. Significant effects on body weight, food consumpti
 
AA Sequence
MVPIHKVQD DTKTLIKTI VTRINDISH TQSVSARQR VTGLDFIPG LHPILSLSK MDQTLAVYQ QILTSLPSQ NVLQIAHDL ENLRDLLHL LAFSKSCSL PQTRGLQKP ESLDGVLEA SLYSTEVVA LSRLQGSLQ DILQQLDLS PEC
Research Interest: Apoptosis, Angiogenesis, Inflammation, Metabolic Regulation and Diabetes
Protein Cross Reactivity: Mouse

Availability: In stock

Size Price Qty
200µg
$80.00
1mg
$195.00
5mg
$500.00