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Recombinant Rat IL-5



Catalog Number : 400-05

Description

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Human
 
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106 units/m
 
AA Sequence
MEIPMSTVV KETLIQLST HRALLTSNE TMRLPVPTH KNHQLCIGE IFQGLDILK NQTVRGGTV EILFQNLSL IKKYIDGQK EKCGEERRK TRHFLDYLQ EFLGVMSTE WAMEV
Research Interest: Innate Immunity, Adaptive Immunity, Immunology, Inflammation, Proliferation and Cell Cycle
Cell Type: B Cells, T Cells
Protein Cross Reactivity: Human

Availability: In stock

Size Price Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00