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Recombinant Rat GM-CSF



Catalog Number : 400-23

Description

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 98% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
Mouse
 
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1.0 x 108 units/mg.
 
AA Sequence
MAPTRSPNP VTRPWKHVD AIKEALSLL NDMRALENE KNEDVDIIS NEFSIQRPT CVQTRLKLY KQGLRGNLT KLNGALTMI ASHYQTNCP PTPETDCEI EVTTFEDFI KNLKGFLFD IPFDCWKPV QK
Research Interest: Innate Immunity, Stem Cell Research, Cancer, Inflammation, Proliferation and Cell Cycle
Cell Type: Monocytes and Macrophages, Treg cells, Endothelial Cells
Protein Cross Reactivity: Mouse

Availability: In stock

Size Price Qty
5µg
$80.00
20µg
$195.00
100µg
$650.00
500µg
$1,950.00
1mg
$3,250.00