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Recombinant Rat FGF-acidic



Catalog Number : 400-29A

Description

FGF-acidic is one of 23 known members of the FGF family.  Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.  FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells.  FGF-acidic has the ability to signal through all the FGF receptors.  Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

Additional Information

Source:
E. Coli
 
Purity:
Above 95% as determined by SDS-PAGE Analysis.
 
Cross Reactivity:
NULL
 
Biological Activity
Determined by a cell proliferation assay using balb/c 3T3 cells.  The expected ED50 is ≤ 0.1 ng/ml, in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 1 x 107 units/mg.
 
AA Sequence
MFNLPLGNY KKPKLLYCS NGGHFLRIL PDGTVDGTR DRSDQHIQL QLSAESAGE VYIKGTETG QYLAMDTEG LLYGSQTPN EECLFLERL EENHYNTYT SKKHAEKNW FVGLKKNGS CKRGPRTHY GQKAILFLP LPVSSD
Research Interest: Stem Cell Research, Cancer, Angiogenesis, Neurosciences, Bone Biology, Proliferation and Cell Cycle
Cell Type: Stem Cells, Endothelial Cells, Neurons
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
10µg
$80.00
50µg
$195.00
100µg
$300.00
500µg
$900.00
1mg
$1,500.00