Recombinant Murine LIGHT
Catalog Number : 315-12
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Testing in progress.
MRLHQRLGD IVAHLPDGG KGSWEKLIQ DQRSHQANP AAHLTGANA SLIGIGGPL LWETRLGLA FLRGLTYHD GALVTMEPG YYYVYSKVQ LSGVGCPQG LANGLPITH GLYKRTSRY PKELELLVS RRSPCGRAN SSRVWWDSS FLGGVVHLE AGEEVVVRV PGNRLVRPR DGTRSYFGA FMV
|Research Interest:||Innate Immunity, Apoptosis, Cancer, Inflammation|
|Cell Type:||Macrophage / Monocyte|
|Protein Cross Reactivity:||Human|