Recombinant Murine Leptin

Grouped product items
SizePrice Qty
200µg
$80.00
1mg
$195.00
5mg
$500.00
Catalog Number : 450-31

description

Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant murine Leptin is a 16.2 kDa protein containing 147 amino acid residues.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Hamster, Human, Pig, Rat
Biological Activity
PeproTech's murine Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg Leptin/gm of body weight f
AA Sequence
MVPIQKVQD DTKTLIKTI VTRINDISH TQSVSAKQR VTGLDFIPG LHPILSLSK MDQTLAVYQ QVLTSLPSQ NVLQIANDL ENLRDLLHL LAFSKSCSL PQTSGLQKP ESLDGVLEA SLYSTEVVA LSRLQGSLQ DILQQLDVS PEC
Research Interest:Apoptosis, Angiogenesis, Inflammation, Metabolic Regulation and Diabetes
Application:FA
Protein Cross Reactivity:Hamster, Human, Pig, Rat
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