Recombinant Human TSG

Grouped product items
Size Price Qty
10µg
$80.00
50µg
$195.00
100µg
$300.00
500µg
$900.00
1mg
$1,500.00
Catalog Number : 120-09

description

Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex. Recombinant human TSG is a 198 amino acid 22.2 kDa protein containing the BMP/TGFβ binding portion of the full length TSG protein.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Mouse
Biological Activity
Determined by its ability to neutralize BMP-6 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is < 2.0 μg/ml of TSG.
AA Sequence
CNKALCASD VSKCLIQEL CQCRPGEGN CSCCKECML CLGALWDEC CDCVGMCNP RNYSDTPPT SKSTVEELH EPIPSLFRA LTEGDTQLN WNIVSFPVA EELSHHENL VSFLETVNQ PHHQNVSVP SNNVHAPYS SDKEHMCTV VYFDDCMSI HQCKISCES MGASKYRWF HNACCECIG PECIDYGSK TVKCMNCMF
Application: FA
Protein Cross Reactivity: Mouse
© BioGems International, Inc. All rights reserved.