Recombinant Human TFF-2

Grouped product items
SizePrice Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00
Catalog Number : 300-59

description

The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al. Am. Journal Respir. Cell Mol. Biol. (2003) 4: 458-464). Recombinant human TFF2 is a 12.0 kDa polypeptide of 107 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
NULL
Biological Activity
Assay #1: Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 µg/ml.

Assay #2: Determined by its ability to chemoattract human MCF-7 cells using a concentra
AA Sequence
AEKPSPCQC SRLSPHNRT NCGFPGITS DQCFDNGCC FDSSVTGVP WCFHPLPKQ ESDQCVMEV SDRRNCGYP GISPEECAS RKCCFSNFI FEVPWCFFP KSVEDCHY
Research Interest:Stem Cell Research, Cancer
Application:FA
Protein Cross Reactivity:NULL
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