Recombinant Human SCGF-α
Catalog Number : 100-22A
SCGF-α and -β are hematopoietic growth factor that exerts their activity at early stages of hematopoiesis. The SCGFs are non-glycosylated species-specific cytokines that can support growth of primitive hematopoietic cells, and in combination with EPO or GM-CSF, promote proliferation or erthroid or myeloid progenitors, respectively. Recombinant human SCGF-α is a 33.9 kDa polypeptide containing 305 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its inhibitory effect on the proliferation of TF-1 cells previously grown in media containing GM-CSF. The ED50 for this effect was observed at 2.5 ng/ml.
GHGARGAER EWEGGWGGA QEEEREREA LMLKHLQEA LGLPAGRGD ENPAGTVEG KEDWEMEED QGEEEEEEA TPTPSSGPS PSPTPEDIV TYILGRLAG LDAGLHQLH VRLHALDTR VVELTQGLR QLRNAAGDT RDAVQALQE AQGRAEREH GRLEGCLKG LRLGHKCFL LSRDFEAQA AAQARCTAR GGSLAQPAD RQQMEALTR YLRAALAPY NWPVWLGVH DRRAEGLYL FENGQRVSF FAWHRSPRP ELGAQPSAS PHPLSPDQP NGGTLENCV AQASDDGSW WDHDCQRRL YYVCEFPF
|Research Interest:||Stem Cell Research, Bone Biology, Proliferation and Cell Cycle|
|Cell Type:||Stem Cells|
|Protein Cross Reactivity:||NULL|