Recombinant Human SCF
Catalog Number : 300-07
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.
Above 98% as determined by SDS-PAGE Analysis.
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
MEGICRNRV TNNVKDVTK LVANLPKDY MITLKYVPG MDVLPSHCW ISEMVVQLS DSLTDLLDK FSNISEGLS NYSIIDKLV NIVDDLVEC VKENSSKDL KKSFKSPEP RLFTPEEFF RIFNRSIDA FKDFVVASE TSDCVVSST LSPEKDSRV SVTKPFMLP PVA
|Research Interest:||Stem Cell Research, Proliferation and Cell Cycle|
|Cell Type:||Stem Cells|
|Protein Cross Reactivity:||Monkey|