Recombinant Human PLGF-2
Catalog Number : 100-56
description
PLGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF-2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-2 also signals through Neuropilin (NP-1) and can bind with high affinity to heparin. Recombinant human PLGF-2 is a 34.0 kDa disulfide-linked homodimeric protein of two 150 amino acid polypeptide chains.
Additional Information
Source: | E. Coli |
Purity: | Above 95% as determined by SDS-PAGE Analysis. |
Cross Reactivity: | NULL |
Biological Activity | Determined by its ability to chemoattract human monocytes of using a concentration range of 5.0-50.0 ng/ml. |
AA Sequence | LPAVPPQQW ALSAGNGSS EVEVVPFQE VWGRSYCRA LERLVDVVS EYPSEVEHM FSPSCVSLL RCTGCCGDE NLHCVPVET ANVTMQLLK IRSGDRPSY VELTFSQHV RCECRPLRE KMKPERRRP KGRGKRRRE KQRPTDCCG DAVPRR |
| Research Interest: | Cancer, Angiogenesis, Inflammation, Proliferation and Cell Cycle |
|---|---|
| Cell Type: | Stem Cells, Endothelial Cells |
| Application: | FA |
| Protein Cross Reactivity: | NULL |