Recombinant Human Pleiotrophin
Catalog Number : 450-15
Pleiotrophin and Midkine are structurally related heparin-binding neurotrophic factors, whose expression is developmentally regulated. The expression pattern of these neurotrophic factors suggests function in neurogenesis, cell migration, secondary organogenetic induction, and mesoderm epithelial interaction. The expression of PTN increases during the process of brain embryogenesis and reaches maximum levels at time of birth. The physiological roles of PTN and Midkine are largely unknown, but these neurotrophins have been implicated in the pathogenesis of neuroblastomas. Recombinant human Pleiotrophin is a 15.4 kDa protein containing 136 amino acid residues and five intra-molecular disulfide bonds.
Above 98% as determined by SDS-PAGE Analysis.
Bacteria, Mouse, Rat
Data not available at this time.
GKKEKPEKK VKKSDCGEW QWSVCVPTS GDCGLGTRE GTRTGAECK QTMKTQRCK IPCNWKKQF GAECKYQFQ AWGECDLNT ALKTRTGSL KRALHNAEC QKTVTISKP CGKLTKPKP QAESKKKKK EGKKQEKML D
|Protein Cross Reactivity:||Bacteria, Mouse, Rat|