Recombinant Human Nesfatin-1
Catalog Number : 300-67
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Originally identified as a hypothalamic neuropeptide, Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic isletsβ-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Recombinant human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by an in vivo assay using healthy wild type male mice (C57BL/6J). Mice were treated via intraperitoneal injection once at a dose of 4μg Nesfatin-1/gm of body weight. Significant effects on body weight and food consumption were ob
VPIDIDKTK VQNIHPVES AKIEPPDTG LYYDEYLKQ VIDVLETDK HFREKLQKA DIEEIKSGR LSKELDLVS HHVRTKLDE L
|Research Interest:||Neurosciences, Metabolic Regulation and Diabetes|
|Protein Cross Reactivity:||NULL|