Recombinant Human Nesfatin-1

Grouped product items
SizePrice Qty
20µg
$80.00
100µg
$195.00
250µg
$385.00
500µg
$660.00
1mg
$1,100.00
Catalog Number : 300-67

description

Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2).  Originally identified as a hypothalamic neuropeptide, Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic isletsβ-cells, gastric endocrine cells and adipocytes.  Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner.  Recombinant human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
NULL
Biological Activity
Determined by an in vivo assay using healthy wild type male mice (C57BL/6J).  Mice were treated via intraperitoneal injection once at a dose of 4μg Nesfatin-1/gm of body weight.  Significant effects on body weight and food consumption were ob
AA Sequence
VPIDIDKTK VQNIHPVES AKIEPPDTG LYYDEYLKQ VIDVLETDK HFREKLQKA DIEEIKSGR LSKELDLVS HHVRTKLDE L
Research Interest:Neurosciences, Metabolic Regulation and Diabetes
Cell Type:Neurons
Application:FA
Protein Cross Reactivity:NULL
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