Recombinant Human Myostatin-Propeptide

Grouped product items
SizePrice Qty
5µg
$80.00
25µg
$195.00
100µg
$700.00
500µg
$3,120.00
1mg
$5,200.00
Catalog Number : 120-12

description

Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin Propeptide exhibits high binding affinity for myostatin and has been shown to be a potent inhibitor of Myostatin. Over-expression of myostatin propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in Myostatin knockout mice. Recombinant Human Myostatin Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Mouse
Biological Activity
Determined by its ability to neutralize the Myostatin inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.01–0.04 μg/ml in the presence of 50 ng/ml Myostatin.
AA Sequence
MNENSEQKE NVEKEGLCN ACTWRQNTK SSRIEAIKI QILSKLRLE TAPNISKDV IRQLLPKAP PLRELIDQY DVQRDDSSD GSLEDDDYH ATTETIITM PTESDFLMQ VDGKPKCCF FKFSSKIQY NKVVKAQLW IYLRPVETP TTVFVQILR LIKPMKDGT RYTGIRSLK LDMNPGTGI WQSIDVKTV LQNWLKQPE SNLGIEIKA LDENGHDLA VTFPGPGED GLNPFLEVK VTDTPKRSR R
Research Interest:Angiogenesis, Bone Biology, Proliferation and Cell Cycle, Metabolic Regulation and Diabetes
Application:FA
Protein Cross Reactivity:Mouse
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