Recombinant Human Maspin
Catalog Number : 130-12
Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability of Maspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells. Recombinant human Maspin is a 42.1 kDa non-glycosylated protein containing 375 amino acid residues.
Above 97% as determined by SDS-PAGE Analysis.
Data not Available.
MDALQLANS AFAVDLFKQ LCEKEPLGN VLFSPICLS TSLSLAQVG AKGDTANEI GQVLHFENV KDIPFGFQT VTSDVNKLS SFYSLKLIK RLYVDKSLN LSTEFISST KRPYAKELE TVDFKDKLE ETKGQINNS IKDLTDGHF ENILADNSV NDQTKILVV NAAYFVGKW MKKFPESET KECPFRLNK TDTKPVQMM NMEATFCMG NIDSINCKI IELPFQNKH LSMFILLPK DVEDESTGL EKIEKQLNS ESLSQWTNP STMANAKVK LSIPKFKVE KMIDPKACL ENLGLKHIF SEDTSDFSG MSETKGVAL SNVIHKVCL EITEDGGDS IEVPGARIL QHKDELNAD HPFIYIIRH NKTRNIIFF GKFCSP
|Research Interest:||Apoptosis, Cancer, Angiogenesis|
|Protein Cross Reactivity:||NULL|