Recombinant Human INSL5/INSL7 Hybrid
Catalog Number : 130-05
The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide bonds. INSL7-INSL5 hybrid contains the B-chain of INSL7 (Relaxin-3), linked to the A-chain of INSL5. The INSL7-INSL5 hybrid protein can specifically activate the G protein coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant INSL7-INSL5 hybrid is a hetero-dimeric 5.2 kDa protein consisting of a 27 amino acid B-chain disulfide linked to a 21 amino acid A-chain.
Above 98% as determined by SDS-PAGE Analysis.
Data not available.
A-chai n:QDL QTLCCTDGC SMTDLSALC
B- chain:RAAPYGVR LCGREFIRA VIFTCGGSR W
|Research Interest:||Neurosciences, Metabolic Regulation and Diabetes|
|Protein Cross Reactivity:||NULL|