Recombinant Human Galectin-1
Catalog Number : 450-39
Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
ACGLVASNL NLKPGECLR VRGEVAPDA KSFVLNLGK DSNNLCLHF NPRFNAHGD ANTIVCNSK DGGAWGTEQ REAVFPFQP GSVAEVCIT FDQANLTVK LPDGYEFKF PNRLNLEAI NYMAADGDF KIKCVAFD
|Research Interest:||Adaptive Immunity, Apoptosis, Immunology, Cancer|
|Cell Type:||T Cells, T Regulatory Cells|
|Protein Cross Reactivity:||NULL|