Recombinant Human Epigen
Catalog Number : 100-51
Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor.
Above 98% as determined by SDS-PAGE Analysis.
Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/ml.
AVTVTPPIT AQQADNIEG PIALKFSHL CLEDHNSYC INGACAFHH ELEKAICRC FTGYTGERC EHLTLTSYA
|Research Interest:||Proliferation and Cell Cycle|
|Protein Cross Reactivity:||Mouse|