Recombinant Human ENA-78 (CXCL5) (8-78 a.a.)
Catalog Number : 300-22B
ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The three naturally occuring variants of human ENA-78; ENA 5-78, ENA 8-78, ENA 9-78, contain 74, 71, and 70 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokines that bind to the CXCR1 and CXCR2 receptors. Recombinant Human ENA-78 is a 7.8 kDa protein consisting of 71 amino acid residues
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.
LRELRCVCL QTTQGVHPK MISNLQVFA IGPQCSKVE VVASLKNGK EICLDPEAP FLKKVIQKI LDGGNKEN
|Research Interest:||Angiogenesis, Inflammation|
|Cell Type:||Macrophage / Monocyte, Endothelial Cells|
|Protein Cross Reactivity:||NULL|