Recombinant Human BAFF Receptor

Grouped product items
SizePrice Qty
10µg
$80.00
50µg
$195.00
100µg
$300.00
500µg
$900.00
1mg
$1,500.00
Catalog Number : 310-13R

description

BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFFR protein.

Additional Information

Source:
E. Coli
Purity:
Above 95% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Mouse
Biological Activity
Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0-4.0 μg/ml in the presence of 1.0μg/ml of human soluble BAFF.
AA Sequence
MRRGPRSLR GRDAPAPTP CVPAECFDL LVRHCVACG LLRTPRPKP AGASSPAPR TALQPQESV GAGAGEAAL PLPG
Research Interest:Innate Immunity, Receptors, Proliferation and Cell Cycle
Cell Type:B Cells
Application:FA
Protein Cross Reactivity:Mouse
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