Recombinant Human BAFF Receptor
Catalog Number : 310-13R
BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFFR protein.
Above 95% as determined by SDS-PAGE Analysis.
Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0-4.0 μg/ml in the presence of 1.0μg/ml of human soluble BAFF.
MRRGPRSLR GRDAPAPTP CVPAECFDL LVRHCVACG LLRTPRPKP AGASSPAPR TALQPQESV GAGAGEAAL PLPG
|Research Interest:||Innate Immunity, Receptors, Proliferation and Cell Cycle|
|Cell Type:||B Cells|
|Protein Cross Reactivity:||Mouse|