Recombinant Human AITRL
Catalog Number : 310-22
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant human soluble AITRL is a 14.4 kDa protein, containing 127 amino acid residues corresponding to the extracellular domain of AITRL.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1.0-10.0 ng/ml.
Please Note: Results may vary with PBMC donors.
METAKEPCM AKFGPLPSK WQMASSEPP CVNKVSDWK LEILQNGLY LIYGQVAPN ANYNDVAPF EVRLYKNKD MIQTLTNKS KIQNVGGTY ELHVGDTID LIFNSEHQV LKNNTYWGI ILLANPQFI
|Research Interest:||Stem Cell Research, Apoptosis, Immunology|
|Cell Type:||T Cells, Endothelial Cells|
|Protein Cross Reactivity:||NULL|