Recombinant Human Activin B
Catalog Number : 120-15
Activin B is a TGF-β family member that exhibits a wide range of biological activities including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands. Activin B, like certain other members of the TGF-β family, signals through the ActRII receptor (Activin Receptor type II). Human Activin B is a 25.6 kDa disulfide-linked homodimer consisting of two βB chains, each containing 115 amino acid residues. *Manufactured using BTI-Tn-5B1-4 cells under license from the Boyce Thompson Institute for Plant Research, Inc
(BTI-Tn-5B1-4) Hi-5 Insect cells*
Above 95% as determined by SDS-PAGE Analysis.
The ED50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
GLECDGRTN LCCRQQFFI DFRLIGWND WIIAPTGYY GNYCEGSCP AYLAGVPGS ASSFHTAVV NQYRMRGLN PGTVNSCCI PTKLSTMSM LYFDDEYNI VKRDVPNMI VEECGCA
|Research Interest:||Stem Cell Research, Apoptosis, Neurosciences, Proliferation and Cell Cycle|
|Cell Type:||T Cells|
|Protein Cross Reactivity:||NULL|