Recombinant Mycoplasma Arginine Deiminase (ADI)
Catalog Number : 150-12
Arginine Deiminase (ADI) is a microbial enzyme from Mycoplasma produced in E.coli. It has high affinity to L-arginine and hydrolyzes L-arginine to citrulline and ammonia. Low concentrations of ADI have been shown to inhibit proliferation in certain cultured cells by arresting the cell cycle in G (1) and/or S phase. Higher concentrations of ADI lead to subsequent apoptosis. Recombinant Mycoplasma Arginine Deiminase is a 46.3 kDa protein consisting of 409 amino acids.
Above 97% as determined by SDS-PAGE Analysis.
Measured by its ability to induce apoptosis in Jurkat cells using a concentration of 100-150 ng/ml.
SVFDSKFKG IHVYSEIGE LESVLVHEP GREIDYITP ARLDELLFS AILESHDAR KEHKQFVAE LKANDINVV ELIDLVAET YDLASQEAK DKLIEEFLE DSEPVLSEE HKVVVRNFL KAKKTSREL VEIMMAGIT KTDLGIEAD HELIVDPMP NLYFTRDPF ASVGNGVTI HYMRYKVRQ RETLFSRFV FSNHPKLIN TPWYYDPSL KLSIEGGDV FIYNNDTLV VGVSERTDL QTVTLLAKN IVANKECEF KRIVAINVP KWTNLMHLD TWLTMLDKD KFLYSPIAN DVFKFWDYD LVNGGAEPQ PVENGLPLE GLLQSIINK KPVLIPIAG EGASQMEIE RETHFDGTN YLAIRPGVV IGYSRNEKT NAALEAAGI KVLPFHGNQ LSLGMGNAR CMSMPLSRK DVKW
|Research Interest:||Apoptosis, Cancer|
|Protein Cross Reactivity:||NULL|