Recombinant Human NP-1
Catalog Number : 300-42
Defensins (α and β) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins which include NP-1, NP-2 and NP-3, are distinguished from the β-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/ml.
ACYCRIPAC IAGERRYGY CIYQGRLWA FCC
|Research Interest:||Innate Immunity|
|Protein Cross Reactivity:||NULL|