Recombinant Rat CNTF

Grouped product items
SizePrice Qty
5µg
$80.00
20µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00
Catalog Number : 450-50

description

CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant rat CNTF is synthesized as a 199 amino acid polypeptide (22.7 kDa) lacking a hydrophobic N-terminal signal for secretion.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Frog, Human, Mouse
Biological Activity
Determined by its ability to stimulate proliferation of human TF-1 cells using a concentration range of 25.0-35.0 ng/ml.
AA Sequence
AFAEQTPLT LHRRDLCSR SIWLARKIR SDLTALMES YVKHQGLNK NINLDSVDG VPVASTDRW SEMTEAERL QENLQAYRT FQGMLTKLL EDQRVHFTP TEGDFHQAI HTLMLQVSA FAYQLEELM VLLEQKIPE NEADGMPAT VGDGGLFEK KLWGLKVLQ ELSQWTVRS IHDLRVISS HQMGISALE SHYGAKDKQ M
Research Interest:Stem Cell Research, Apoptosis, Angiogenesis, Neurosciences, Bone Biology, Inflammation, Metabolic Regulation and Diabetes
Cell Type:Stem Cells, Neurons
Application:FA
Protein Cross Reactivity:Frog, Human, Mouse
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