Animal-Free Recombinant Human NT-4
NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues). Manufactured using all non-animal reagents.
Above 98% as determined by SDS-PAGE Analysis.
Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
GVSETAPAS RRGELAVCD AVSGWVTDR RTAVDLRGR EVEVLGEVP AAGGSPLRQ YFFETRCKA DNAEEGGPG AGGGGCRGV DRRHWVSEC KAKQSYVRA LTADAQGRV GWRWIRIDT ACVCTLLSR TGRA
|Research Interest:||Stem Cell Research, Neurosciences, Metabolic Regulation and Diabetes|
|Protein Cross Reactivity:||NULL|