Animal-Free Recombinant Human VEGF 165
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains. Manufactured using all non-animal reagents.
Above 98% as determined by SDS-PAGE Analysis.
Cow, Guinea Pig, Hamster, Mouse, Pig, Rabbit, Rat, Sheep, Trout
Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.
APMAEGGGQ NHHEVVKFM DVYQRSYCH PIETLVDIF QEYPDEIEY IFKPSCVPL MRCGGCCND EGLECVPTE ESNITMQIM RIKPHQGQH IGEMSFLQH NKCECRPKK DRARQENPC GPCSERRKH LFVQDPQTC KCSCKNTDS RCKARQLEL NERTCRCDK PRR
|Research Interest:||Stem Cell Research, Cancer, Angiogenesis, Inflammation, Proliferation and Cell Cycle|
|Cell Type:||Macrophage / Monocyte, Stem Cells|
|Protein Cross Reactivity:||Cow, Guinea Pig, Hamster, Mouse, Pig, Rabbit, Rat, Sheep, Trout|