Recombinant Rat IL-7
Catalog Number : 400-07
description
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
Additional Information
Source:
|
E. Coli
|
Purity:
|
Above 98% as determined by SDS-PAGE Analysis.
|
Cross Reactivity:
|
Mouse
|
Biological Activity
|
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
|
AA Sequence
|
MDCHIKDKD GKAFGSVLM ISINQLDKM TGTDSDCPN NEPNFFKKH LCDDTKEAA FLNRAARKL RQFLKMNIS EEFNDHLLR VSDGTQTLV NCTSKEEKT IKEQKKNDP CFLKRLLRE IKTCWNKIL KGSI
|
Research Interest: | Innate Immunity, Adaptive Immunity, Stem Cell Research, Cancer, Inflammation |
---|---|
Cell Type: | B Cells, T Cells, Stem Cells |
Application: | FA |
Protein Cross Reactivity: | Mouse |