Recombinant Rat IL-7
Catalog Number : 400-07
description
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
Additional Information
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Source:
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E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity:
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Mouse
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Biological Activity
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The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
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AA Sequence
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MDCHIKDKD GKAFGSVLM ISINQLDKM TGTDSDCPN NEPNFFKKH LCDDTKEAA FLNRAARKL RQFLKMNIS EEFNDHLLR VSDGTQTLV NCTSKEEKT IKEQKKNDP CFLKRLLRE IKTCWNKIL KGSI
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| Research Interest: | Innate Immunity, Adaptive Immunity, Stem Cell Research, Cancer, Inflammation |
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| Cell Type: | B Cells, T Cells, Stem Cells |
| Application: | FA |
| Protein Cross Reactivity: | Mouse |