Recombinant Rat IL-5
Catalog Number : 400-05
description
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
Additional Information
|
Source:
|
E. Coli
|
|
Purity:
|
Above 98% as determined by SDS-PAGE Analysis.
|
|
Cross Reactivity:
|
Human
|
|
Biological Activity
|
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106 units/m
|
|
AA Sequence
|
MEIPMSTVV KETLIQLST HRALLTSNE TMRLPVPTH KNHQLCIGE IFQGLDILK NQTVRGGTV EILFQNLSL IKKYIDGQK EKCGEERRK TRHFLDYLQ EFLGVMSTE WAMEV
|
| Research Interest: | Innate Immunity, Adaptive Immunity, Immunology, Inflammation, Proliferation and Cell Cycle |
|---|---|
| Cell Type: | B Cells, T Cells |
| Application: | FA |
| Protein Cross Reactivity: | Human |