Recombinant Rat IL-15
Catalog Number : 400-24
IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.
Above 98% as determined by SDS-PAGE Analysis.
The ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 105 units/mg.
MNWIDVRYD LEKIESLIQ FIHIDTTLY TDSDFHPSC KVTAMNCFL LELQVILHE YSNMTLNET VRNVLYLAN STLSSNKNV IESGCKECE ELEERNFTE FLQSFIHIV QMFINTS
|Research Interest:||Innate Immunity, Adaptive Immunity, Stem Cell Research, Apoptosis, Immunology, Cancer, Inflammation|
|Cell Type:||NK and NKT Cells, T Cells|
|Protein Cross Reactivity:||Human, Mouse|