Recombinant Rat IL-15

Grouped product items
SizePrice Qty
2µg
$80.00
10µg
$195.00
100µg
$780.00
500µg
$2,340.00
1mg
$3,900.00
Catalog Number : 400-24

description

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Human, Mouse
Biological Activity
The ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 105 units/mg.
AA Sequence
MNWIDVRYD LEKIESLIQ FIHIDTTLY TDSDFHPSC KVTAMNCFL LELQVILHE YSNMTLNET VRNVLYLAN STLSSNKNV IESGCKECE ELEERNFTE FLQSFIHIV QMFINTS
Research Interest:Innate Immunity, Adaptive Immunity, Stem Cell Research, Apoptosis, Immunology, Cancer, Inflammation
Cell Type:NK and NKT Cells, T Cells
Application:FA
Protein Cross Reactivity:Human, Mouse
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