Recombinant Murine IL-5
Catalog Number : 215-15
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
Above 98% as determined by SDS-PAGE Analysis.
The ED50was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105units/mg.
MEIPMSTVV KETLTQLSA HRALLTSNE TMRLPVPTH KNHQLCIGE IFQGLDILK NQTVRGGTV EMLFQNLSL IKKYIDRQK EKCGEERRR TRQFLDYLQ EFLGVMSTE WAMEG
|Research Interest:||Innate Immunity, Adaptive Immunity, Immunology, Inflammation, Proliferation and Cell Cycle|
|Cell Type:||B Cells, T Cells|
|Protein Cross Reactivity:||Human|