Recombinant Murine IL-5

Grouped product items
SizePrice Qty
5µg
$80.00
25µg
$195.00
100µg
$600.00
500µg
$1,800.00
1mg
$3,000.00
Catalog Number : 215-15

description

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
Human
Biological Activity
The ED50was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 2.0 ng/ml, corresponding to a specific activity of > 5 x 105units/mg.
AA Sequence
MEIPMSTVV KETLTQLSA HRALLTSNE TMRLPVPTH KNHQLCIGE IFQGLDILK NQTVRGGTV EMLFQNLSL IKKYIDRQK EKCGEERRR TRQFLDYLQ EFLGVMSTE WAMEG
Research Interest:Innate Immunity, Adaptive Immunity, Immunology, Inflammation, Proliferation and Cell Cycle
Cell Type:B Cells, T Cells
Application:FA
Protein Cross Reactivity:Human
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