Recombinant Murine IL-33
Catalog Number : 210-33
description
IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant murine IL-33 is a 17.5 kDa protein containing 158 amino acid residues.
Additional Information
Source: | E. Coli |
Purity: | Above 98% as determined by SDS-PAGE Analysis. |
Cross Reactivity: | NULL |
Biological Activity | The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106units/mg. |
AA Sequence | SIQGTSLLT QSPASLSTY NDQSVSFVL ENGCYVINV DDSGKDQEQ DQVLLRYYE SPCPASQSG DGVDGKKLM VNMSPIKDT DIWLHANDK DYSVELQRG DVSPPEQAF FVLHKKSSD FVSFECKNL PGTYIGVKD NQLALVEEK DESCNNIMF KLSKI |
| Research Interest: | Immunology, Inflammation |
|---|---|
| Application: | FA |
| Protein Cross Reactivity: | NULL |