Recombinant Human IL-9

Grouped product items
SizePrice Qty
2µg
$80.00
10µg
$195.00
100µg
$1,040.00
500µg
$3,120.00
1mg
$5,200.00
Catalog Number : 200-09

description

IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant human IL-9 is a 14.0 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.

Additional Information

Source:
E. Coli
Purity:
Above 98% as determined by SDS-PAGE Analysis.
Cross Reactivity:
NULL
Biological Activity
The ED50 as determined by the dose-dependent proliferation of human M07e cells was ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
AA Sequence
MQGCPTLAG ILDINFLIN KMQEDPASK CHCSANVTS CLCLGIPSD NCTRPCFSE RLSQMTNTT MQTRYPLIF SRVKKSVEV LKNNKCPYF SCEQPCNQT TAGNALTFL KSLLEIFQK EKMRGMRGK I
Research Interest:Adaptive Immunity, Cancer, Proliferation and Cell Cycle
Cell Type:T Cells
Application:FA
Protein Cross Reactivity:NULL
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